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More hunger means overeating
Plus, injectable medications must be refrigerated and can be hard to travel with
This pushes your body to not just maintain muscle but to potentially build new tissue even during a caloric deficit
Some semaglutide medications are not suited to everyone
These negative results are similar to the Exenatide Phase 3 trial in Parkinsons disease, which I summarized in an earlier entry: Semaglutide at the tested dose, in this population, failed to affect cognitive decline, and biomarker changes were minimal or ambiguous
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